The utility of C-reactive protein in the diagnosis and monitoring of the pediatric patient - review of recent literature data
The utility of C-reactive protein in the diagnosis and monitoring of the pediatric patient - review of recent literature data

Summary/Abstract: Certain laboratory parameters can be used to quickly guide the diagnosis of a child with signs of acute illness, and C-reactive protein (CRP) is among the best characterized such biomarkers. We conducted a systematic literature search using PubMed to identify the most recent original articles or reviews published between 1 January 2016 and 30 September 2021, on the topic of the clinical utility of CRP in pediatric practice, using the following two-word combinations: “C-reactive protein” and “children”, and “CRP” and “children”. Although it does not have a high specificity to differentiate between viral or bacterial etiology, CRP can be used successfully in the clinic in the follow-up of children with acute infectious diseases, including newborns. We have identified in the literature an association between obesity, metabolic disorders, neuro-psychological status and CRP value. In conclusion the latest data show that CRP is an easy and reliable marker, but its value must be integrated into the patient's clinical context.

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