Dikkat Eksikliği Hiperaktivite Bozukluğu ile Otonom Sinir Sisteminin İlişkisi: Bir Güncelleme
Association between Attention Deficit Hyperactivity Disorder and Autonomic Nervous System: An Update

Summary/Abstract: This article constitutes a review of the research on the relationship between Attention Deficit Hyperactivity Disorder (ADHD) and autonomic nervous system (ANS) functionality. It also explores the possibility of using heart rate variability (HRV) to investigate the link between ADHD and autonomic dysfunction. One line of inquiry that has been the focus of sudies on the pathogensis of ADHD is the dysfunction of the autonomic system. The physiological measurements used to evaluate autonomic dysfunction are concentrated in the cardiovascular system. Databases were searched to identify studies published prior to August 2020. Studies that examined ANS with regard to medication use/treatment were excluded, while those related to ADHD etiopathogenesis were prioritized. In the present article, 52 studies, three of which were systematic reviews and meta-analyses, were evaluated. In general, although the etiopathogenetic association between ADHD and autonomic dysfunction (especially reduced parasympathetic activity) is remarkable, the findings are nonetheless contradictory. Heterogeneity, subtypes, and comorbidities in cases of ADHD appear to complicate the relationship with autonomic dysfunction.

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