Laboratory Diagnosis and Treatment of Diffuse Large B-cell Lymphoma Cover Image

Laboratórna diagnostika a liečba difúzneho veľkobunkového lymfómu z B- buniek
Laboratory Diagnosis and Treatment of Diffuse Large B-cell Lymphoma

Author(s): Ivan Ondrášik, Marika Lorenčíková, Jaromír Tupý, Miriam Tupá, Elena Martišová, Janka Filická, Katarína Ondrášiková
Subject(s): Health and medicine and law
Published by: VERBUM - vydavateľstvo Katolíckej univerzity v Ružomberku
Keywords: Diffuse large B-cell lymphoma (DLBCL); Histology; Morphology; Immunophenotyping; Cytogenetics; Molecular biology; CAR T-cell therapy

Summary/Abstract: In the review article, we analyze the laboratory diagnosis of diffuse large B-cell lymphoma (DLBCL). We focus mainly on morphological diagnosis, which we also illustrate. Next, we approach the immunophenotypic, cytogenetic and molecular-biological diagnosis of this aggressive lymphoma. We also point to the treatment of DLBCL with a sketch of the current CAR T-cell therapy, which may be a hope for patients if previous procedures fail.

  • Issue Year: XV/2023
  • Issue No: 1
  • Page Range: 16-21
  • Page Count: 6
  • Language: Slovak
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