Laboratórna diagnostika a liečba difúzneho veľkobunkového lymfómu z B- buniek
Laboratory Diagnosis and Treatment of Diffuse Large B-cell Lymphoma
Author(s): Ivan Ondrášik, Marika Lorenčíková, Jaromír Tupý, Miriam Tupá, Elena Martišová, Janka Filická, Katarína OndrášikováSubject(s): Health and medicine and law
Published by: VERBUM - vydavateľstvo Katolíckej univerzity v Ružomberku
Keywords: Diffuse large B-cell lymphoma (DLBCL); Histology; Morphology; Immunophenotyping; Cytogenetics; Molecular biology; CAR T-cell therapy
Summary/Abstract: In the review article, we analyze the laboratory diagnosis of diffuse large B-cell lymphoma (DLBCL). We focus mainly on morphological diagnosis, which we also illustrate. Next, we approach the immunophenotypic, cytogenetic and molecular-biological diagnosis of this aggressive lymphoma. We also point to the treatment of DLBCL with a sketch of the current CAR T-cell therapy, which may be a hope for patients if previous procedures fail.
Journal: Zdravotnícke štúdie
- Issue Year: XV/2023
- Issue No: 1
- Page Range: 16-21
- Page Count: 6
- Language: Slovak