Current understanding of Alzheimer's disease
Current understanding of Alzheimer's disease

Summary/Abstract: Worldwide, and disproportionately among the aged, Alzheimer's disease (AD) is a neurological disease that worsens over time and is the main cause of dementia. It begins with a gradual loss of cognitive abilities and memory, progresses to changes in behavior, and culminates in the death of neurons and dementia. A number of promising novel AD therapies, however, are in the works. This article summarizes current theories on the origin of Alzheimer's disease and focuses on recent developments in treatment, including immunotherapy, gene therapy, peptidomimetics, metal chelators.

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