Beta blocker induced notorious psychiatric combination: psychosis, depression, and suicide
Beta blocker induced notorious psychiatric combination: psychosis, depression, and suicide

Summary/Abstract: The literature review shows that the most common psychiatric manifestation of beta adrenoreceptor blockers is depression, fatigue, and erectile dysfunction. There was one case reported in the 1970s about psychosis-induced by beta adrenoreceptor blocker. This case report is the only one of its kind reporting an association between psychosis and beta adrenoreceptor blockers uses. The case we would like to report is unique in its kind because it can be considered to be the second in literature to convey the rare, but detrimental, side effect profile of beta adrenoreceptor blockers: psychosis. Furthermore, our case report is demonstrating evidence of psychosis co-existing with worsening depressive symptoms, and emerging suicidal thoughts. Another large cohort study was conducted in the 1990s that assessed the risk of suicide in 58, 529 users of B-adrenoceptor blockers, calcium channel blockers, and angiotensin converting enzyme inhibitors (ACEIs). One hundred and forty suicide cases were reported in this study, and it was significant in users of B-adrenoceptor blockers. This study and further literature concluded that b-adrenoreceptor blockers were associated with increased risk of suicide. However, calcium channel blockers and ACEIs were not associated with increased suicide risk.

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