Depression may be a complication of various brain disorders: neuroimaging evidence
Depression may be a complication of various brain disorders: neuroimaging evidence

Summary/Abstract: Depression is a complex multifactorial psychiatric disorder affecting a large number of people. The heightened risk of suicide and economic burden make depression a major health concern.1 Compelling data suggest that higher mental functions, executive function, awareness, planning, strategic thinking, initiative and processing sensory input are the domain of prefrontal cortex function and in particular Bradman areas 8,9,10,42 and 46.2 It is noteworthy that the core depression symptoms of diminished joy, energy, self-confidence, problem-solving ability and ability to make strategic plans are also manifestations of diminished prefrontal cortex function.

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