HEMORADIOTERAPIJA TUMORA GLAVE I VRATA
CHEMO RADIOTHERAPY OF HEAD AND NECK TUMORS

Summary/Abstract: Aim: To explore chemo radiotherapy and targeted therapies in the treatment fortumors of the head and neck. We will show the results of incidence and treatment options for patients treated in the Clinic for oncology in Sarajevo from 2010 to2014. Methods and material: We searched the Internet for treatments with chemo and radiotherapy and targeted therapies in head and neck tumors. We considered studies phase II and III, and proposals of NCI and EORT for new standards intreatment of head and neck tumors. In the Clinic of Oncology Sarajevo we treated 480 patients with head and neck tumors. Most of the treatments were radio therapy with standard fractionations of 2Gy/day to total dose of 65 to 70Gy. Some patients also received chemotherapy. Results: In head and neck tumors Cisplatin isthe most often researched chemotherapy. Given concomitantly with radiotherapy it shows better results in both, local control and survival of patients. Targeted therapies show similar results in local control and survival but with less toxicity Grade 3/4. In the Clinic of Oncology in Sarajevo retrospective analysis of results shows that chemo and radiotherapy is the new standard for the treatment of advanced head and neck tumors

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