Activity of cytoplasmic NADP-dependent dehydrogenases and cytochromes Р-450 and b5 levels in a rat’s liver under introduction of cobalt and mercury chlorides Cover Image

Активность цитоплазматических nadp-зависимых дегидрогеназ и содержание цитохромов р-450 и в5 в печени крыс при введении хлорида кобальта и хлорид
Activity of cytoplasmic NADP-dependent dehydrogenases and cytochromes Р-450 and b5 levels in a rat’s liver under introduction of cobalt and mercury chlorides

Author(s): G. V. Ganusova
Subject(s): Health and medicine and law, Sociobiology
Published by: Дніпропетровський національний університет імені Олеся Гончара
Keywords: cytoplasmic NADP; rat’s liver; cobalt and mercury chlorides;

Summary/Abstract: Influence of the cobalt chloride and mercury chloride on the activity of cytoplasmic NADP-dependent dehydrogenases and cytochromes level in a rat’s liver was studied after 0.5, 2 and 14 hours of introduction. Cobalt chloride and mercury chloride result in decrease of the microsomal cytochromes P-450 and b5 contents in 14 hours. Reduction of the glucose 6-phosphate dehydrogenase and malate dehydrogenase activities in half an hour after cobalt chloride introduction is ascertained. The mercury chloride did not influence on the activity of NADP-dependent dehydrogenases.

  • Issue Year: 14/2006
  • Issue No: 2
  • Page Range: 54-58
  • Page Count: 5
  • Language: Russian
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