Активность цитоплазматических nadp-зависимых дегидрогеназ и содержание цитохромов р-450 и в5 в печени крыс при введении хлорида кобальта и хлорид
Activity of cytoplasmic NADP-dependent dehydrogenases and cytochromes Р-450 and b5 levels in a rat’s liver under introduction of cobalt and mercury chlorides
Author(s): G. V. GanusovaSubject(s): Health and medicine and law, Sociobiology
Published by: Дніпропетровський національний університет імені Олеся Гончара
Keywords: cytoplasmic NADP; rat’s liver; cobalt and mercury chlorides;
Summary/Abstract: Influence of the cobalt chloride and mercury chloride on the activity of cytoplasmic NADP-dependent dehydrogenases and cytochromes level in a rat’s liver was studied after 0.5, 2 and 14 hours of introduction. Cobalt chloride and mercury chloride result in decrease of the microsomal cytochromes P-450 and b5 contents in 14 hours. Reduction of the glucose 6-phosphate dehydrogenase and malate dehydrogenase activities in half an hour after cobalt chloride introduction is ascertained. The mercury chloride did not influence on the activity of NADP-dependent dehydrogenases.
Journal: Biosystems Diversity
- Issue Year: 14/2006
- Issue No: 2
- Page Range: 54-58
- Page Count: 5
- Language: Russian