ІСТОРИЧНІ ЕТАПИ НАУКОВИХ ДОСЛІДЖЕНЬ КАФЕДРИ МІКРОБІОЛОГІЇ ТА ВІРУСОЛОГІЇ БУКОВИНСЬКОГО ДЕРЖАВНОГО МЕДИЧНОГО УНІВЕРСИТЕТУ
HISTORICAL STAGES OF STUDY AND INVESTIGATION OF ANTIMICROBIAL ACTIVITY OF NEW SYNTHETIC COMPOUNDS BY THE STAFF OF DEPARTMENT OF MICROBIOLOGY AND VIROLOGY OF BUKOVINIAN STATE MEDICAL UNIVERSITY

Summary/Abstract: The aim of study: inform the wide of medical workers with major studies of scientific researches of the department of microbiology and virology. Methods of investigation: historical, biographic and systematic analysis. Scientific novelty: Since 1965, the department is working on a single research problem: "The study of antimicrobial activity of quaternary ammonium compounds and other new chemotherapeutic drugs." There have been studied various quaternary nitrogen compounds, phosphonium derivatives, azomethines, salts of quinaldynium and others. The results of the research were a study and implementation in public health in practice of new antimicrobial drug - decamethoxinum, derived quaternary ammonium compounds (H.K.Paliy, H.A.Troyan, K.I.Tyschenko). In the department there were investigated antibacterial (Patratiy V.K., Prodanchuk M.G.,, Burdeynyuk I.P., Dejneka S.E.), antifungals (Sinchenko V.G.) and antiviral (Patratiy V.K., Prodanchuk M.G.) properties of quaternary ammonium and phosphonium compounds, modified azole heterocyclic compounds: imidazole, selenazole, oxazole, thiazole; quinoline, quinoxalines, acetonitriles, pyroles, complexes of polycyclic condensed systems, furan derivatives, silicon organic compounds and many others. Сonclusions. The article describes a brief historical development of the department. Major stages of scientific researches since the formation of the department till nowadays were analyzed.

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