Pain perception in zebrafish (Danio rerio) : possible relevance for human neuropsychiatric studies Cover Image

Pain perception in zebrafish (Danio rerio) : possible relevance for human neuropsychiatric studies
Pain perception in zebrafish (Danio rerio) : possible relevance for human neuropsychiatric studies

Author(s): Mădălina-Andreea Robea, Mircea Nicoară, Ștefan-Adrian Strungaru, Alin Ciobîcă, Gabriel Plăvan
Subject(s): Psychology, Neuropsychology, Health and medicine and law
Published by: Editura Sedcom Libris Iasi
Keywords: nociception; pain; behaviour; zebrafish; noxious stimulus;

Summary/Abstract: Despite the evolutionary distance between fish and humans, in the last period there is an explose on studying fish responses at different human diseases and not only that. This fact is possible due to the existence of a certain base from where all the component structures of humans evolved. Pain is a sensation which, many times, induces a certain mood and it is often considered as a disease symptom . The perception of pain requires particular nervous network which was discovered in fish and presents similarity with that found in humans after numerous experiments, where fish were tested with various stimulus. In this review, we described the mechanism of pain perception behind a previous exposure to a noxious stimulus on humans and then on fish, especially zebrafish which is known nowadays as an adequate animal model, as this could have further relevance for human neuropsychiatric diseases, as our group previously described several times before.

  • Issue Year: 78/2018
  • Issue No: 3
  • Page Range: 27-35
  • Page Count: 9
  • Language: English