Identification of 677C>T Polymorphism of LRP1 Gene by PCR-RFLP Method
Identification of 677C>T Polymorphism of LRP1 Gene by PCR-RFLP Method
Author(s): Amela Jusić, Aldijana Avdić, Vesna Hadžiavdić, Inela Junuzović, Dženita KurtčehajićSubject(s): ICT Information and Communications Technologies
Published by: UIKTEN - Association for Information Communication Technology Education and Science
Keywords: LRP1 gene; PCR-RFLP method;
Summary/Abstract: The 677 C>T (rs1799986) polymorphism is located at position 677 in exon 3 of the LRP1 gene. The aim of this study was to determine the allele andgenotype frequencies of the polymorphism in Bosnian population. The study included 100 unrelated healthy individuals. Genotyping of 677 C>T polymorphism ofthe LRP1 gene was performed with PCR-RFLP method. The most frequent allele was the C allele (91%), while the T allele was represented by 9%. Theseresults suggested that presence of the 677 C>T polymorphism of the LRP1 gene in our population should be a base for further case-control association orpopulation genetics studies.
Journal: TEM Journal
- Issue Year: 7/2018
- Issue No: 4
- Page Range: 803-807
- Page Count: 5
- Language: English