Is it aortic valve sclerosis a predictor for bilateral renal artery stenosis outcome in geriatric population?
Is it aortic valve sclerosis a predictor for bilateral renal artery stenosis outcome in geriatric population?

Summary/Abstract: Introduction: It’s wellknown the fact that aortic valve sclerosis (AVS) is a predictor ofincreased cardiovascular risk factor, but it’s implication in renal artery stenosis (RAS)outcome hasn’t been deepened.Objective: The purpose was to establish a correlation between aortic valve sclerosis ingeriatric patients, renal artery stenosis, vascular events and depression.Methods: We’ve included 32 patients with bilateral RAS; 17 patients had also AVS (group A)and 15 patients were the control group, without AVS (group B). During 24 months, wefollowed the occurrence of cardiovascular events (myocardial infarction and stroke), renalfailure (serum creatinine level), heart failure aggravation (echocardiographical parameters)and depression.Results: During 24 months, the incidence of acute vascular events was higher among group A,comparatively to group B (confidence interval CI 95%: 2.85- 2.25).Renal function was animportant parameter in our study; we’ve observed higher serum creatinine levels for thepatients with AVS, even both groups had renovascular arterial hypertension due to bilateralRAS and a physiopathological tendency to renal dysfunction (CI 95%: 2.41 - 2.16). The heartfailure prevalence was more prominent in group A than group B, both systolic and diastolictypes (CI 95%: 2.76-2.3). High sensitivity C reactive protein (hs- CRP) levels were higher forgroup A (CI 95% : 2.62-2.41).Different severity of depression were more frequent in group A.Conclusions: Our study revealed the fact that AVS promotes unfavorable evolution for thepatients with bilateral RAS, extending its influence towards ‘’target’’ vascular territories andtowards depression outcome.

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