SUDĖTINĖS GEOMETRINĖS STRUKTŪROS BIOJUTIKLIŲ KOMPIUTERINIS MODELIAVIMAS*
COMPUTER -AIDED MODELING OF BIOSENSORS WITH A COMPLEX GEOMETRICAL STRUCTURE

Summary/Abstract: Biosensors are analytical devices used to measure the concentration of substances. When developing new biosensors, a lot of experiments are needed to be performed. Mathematical modeling of biosensors is used to decrease the number of physical experiments. Models of biosensors are usually created for each structurally unique biosensor by defining its mathematical model and the corresponding numerical approximation. Equations of the numerical model are then solved using computer programs, usually created for a particular model of the biosensor. Each of these steps requires a great attention and should be automated. The article presents a metamodelfor a biosensor, enabling one to define models of biosensors in domain-specific terms. The proposed metamodel describes biosensor models, defined in the two-dimensional space and including definitions of the structure of a biosensor, its geometrical properties, reactions and diffusion processes taking place in it. Upon defining the metamodel, we compiled the computer software able to create computer models for biosensors from the models formulated according to the proposed metamodel. The metamodel was practically used to define a model for a real biosensor, and the biosensor modeling software was used to simulate its operation.

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