Biojutiklio su alosterinio fermento sluoksniu komPiuterinis modeliavimas
Computational modeling of a biosensor based on allosteric enzyme layer

Summary/Abstract: In this study computational modeling of bio-sensors with allosteric enzyme is investigated. The operation of the bio-sensor was simulated using non-stationary reaction-diffusion equations. This model involves the allosteric enzyme layer where the allosteric enzyme reactions as well as the mass transport by diffusion take place. In the convective region the analyzed concentration is assumed to be constant. Numeric experiments show that developed mathematical model is suitable for a modeling of bio-sensors with an allosteric enzyme layer. It was found, that the Michaelis-Menten kinetic models could be applied for bio-sensors with allosteric enzyme by increasing the enzyme concentration and enzyme layer thickness.

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