Синаптическая пластичность головного мозга сибирского осетра при изменении параметров информационной среды
Synaptic brain plasticity of Siberian sturgeon in changing the parameters of informational environment

Summary/Abstract: This article presents the results of experimental modeling which demonstrated the influence of fluctuations in hydrothermal regime and lead levels exceeding in the environment on the state of terminal parts of forebrain neurons in Siberian sturgeon. The purpose of this work is to investigate synaptic forebrain plasticity in Siberian sturgeon within changing parameters of informational environment. According to the obtained results, an influence of environmental factors leads to adaptive remodeling of synaptic means. Throughout thirty days of exposure the adaptive change of synaptoarchitectonics has been identified as incomplete. This was proved by the methods of morphology and physiology on the cellular and ontogenetic levels. The significant role of free radical mechanism was demonstrated on the realization of synaptic forebrain plasticity in Siberian sturgeon. The use of the new generation multifunctional sulfur-containing antioxidant «Thiophane» during the realization of reactions of the adaptation syndrome allows to regulate the level of free radical activity in neurons. In conclusion, the authors justify the possibility of using antioxidant «Thiophane» for control of synaptic forebrain plasticity in sturgeons in conditions of changing the environmental factors.

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