Вплив ліпосомних форм сполук ренію та цис-платину на тiол-дисульфідне співвідношення у крові щурів
Influence of liposome forms of the rhenium compounds and cis-platin on thiol-disulfide coefficient in the rats’ blood
Author(s): I. V. Klenina, М. V. Gorila, N. I. ShtemenkoSubject(s): Sociobiology
Published by: Дніпропетровський національний університет імені Олеся Гончара
Keywords: rats’ blood; liposome forms; rhenium compounds;
Summary/Abstract: Thiol-disulfide coefficient (TDC) and its different modifications in model in vivo were studied. Introduction of the liposome forms of cluster rhenium compounds with organic ligands (CROL) leads to both TDC increasing and to the constancy of the TDC. Thus, CROLs aren’t toxic agents and some compounds could mobilize organisms’ thiol defence system. Liposome form of cis-platin leads to the TDC decreasing. Important CROL capacities for its future medical treatment practice were shown.
Journal: Biosystems Diversity
- Issue Year: 16/2008
- Issue No: 2
- Page Range: 65-68
- Page Count: 4
- Language: Ukrainian