Gender differences in circulatory adjustment to head-up tilt test in health
Gender differences in circulatory adjustment to head-up tilt test in health

Summary/Abstract: Background: A tilt table test is a useful, non-invasive technique that has been used for the last few decades todetect autonomic failure. The response to tilting may vary physiologically between sexes.Aim of the study: To assess the gender-specific changes in cardiovascular response to a tilt test in healthy subjects.Material and methods: This experimental study was conducted on 90 healthy males and females aged 18–60years, from 2019 to 2020. Forty-five male subjects and 45 female subjects were included. Using a motorizedtilt table, a tilt table test was performed at 60 degrees for 10 minutes. An automatic sphygmomanometer wasused to measure blood pressure (BP), and heart rate (HR) and a pulse oximeter was used for the measurementof peripheral capillary oxygen saturation (SpO2). An independent sample t test, a multiple regression analysisand a chi squared test were conducted for statistical analyses.Results: A significantly greater drop in systolic blood pressure (SBP) was observed in females, compared tomales after tilting. In 5.5% of the subjects, orthostatic intolerance occurred, but there were no significant ageor gender- specific differences in subjects with orthostatic intolerance.Conclusions: This study concluded that in response to tilting, cardiovascular response was less pronouncedin females.

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