Vyšetrenie sympatikovej inervácie myokardu u diabetikov, parkinsonikov a pacientov s dilatačnou kardiomyopatiou pomocou Adreview (123I)
Examination of Sympathetic Myocardial Innervation in Diabetics, Parkinsonians and Patients with Ddilated Cardiomyopathy using Adreview (123I)
Author(s): Anton Lacko, Ján Straka, Antonín Hruboň, Gabriela Muchová, Lenka Krajčová, Katarína Hrušková, Dominik TimkoSubject(s): Health and medicine and law
Published by: VERBUM - vydavateľstvo Katolíckej univerzity v Ružomberku
Keywords: Autonomic nervous system; Heart rate variability; Adreview; Diabetes mellitus; Parkinson´s disease; Dilated cardiomyopathy;
Summary/Abstract: Autonomic nervous system has an important rule in cardiovascular system regulation. its dysfunction can be found in many cardiac diseases, ischaemic heart disease, diabetes mellitus, Parkinson‘s disease, cardiomyopathies, etc. Examination by Adreview (123I) (metaiodbenzylguanidin-MiBG) enables to determine concetration of sympathetic nervous system receptors in mycardial muscle and reveal even asymptomatic stage of cardiovascular autonomic dysfunction. Adreview (123I) is a metabolic analogue of adrenergic blocker guanethidin. There is no enzymatic degradation in nervous synapses in contrary to noradrenaline.
Journal: Zdravotnícke štúdie
- Issue Year: XII/2020
- Issue No: 2
- Page Range: 3-6
- Page Count: 4
- Language: Slovak
