Periocular non-melanoma skin tumours of the eyelids - review
Periocular non-melanoma skin tumours of the eyelids - review

Summary/Abstract: Introduction: Basal cell carcinoma (BCC) is the most common tumour of the eyelids and periocular region. The incidence of BCC of the eyelids (C44.1 ICD-10-CM) is gradually increasing worldwide. Basal cell carcinoma represents 90 % of malignant tumours of the eyelids, predominantly in the male population Squamous cell carcinoma, sebaceous carcinoma, Merkel cell tumour, Kaposi’s sarcoma or primary lymphoma are found less often in the periocular area. Research objectives: The aim of this article is to analyse the epidemiology, aetiopathogenesis, clinical attributes, diagnostics, histopathology, recurrence, prognostic factors and management of BCC. Core of work: Non-melanoma skin tumours are the most widespread malignancies in the Caucasian population. Standardised incidence of diagnosis C44 (dg. C44.) in the period 1997–2 012 in Slovakia ranged from 35.05 to 73.9 cases per 100,000 inhabitants. Dependency on gender, age, and tumour incidence have been demonstrated in several studies. A definitive diagnosis can only be established on the basis of a histopathological examination. The primary treatment modality for BCC is surgical resection. Advanced lesions require extensive surgical interventions and other available treatment modalities. We can consider the apoptotic index, the expression of Bcl-2, as an unexplained prognostic factor of BCC recurrence. Conclusion: Within the context of onco-ophthalmology, increased attention must be given to periocular malignant tumours. Multidisciplinary and patient co-operation in the field of cancer is essential, improving early diagnosis, treatment and survival of patients. Patient management requires an individualised approach.

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