Von Willebrandova choroba
Von Willebrand Disease
Author(s): Lenka Popelková, Jaromír Tupý, Marika Lorenčíková, Oľga HusarčíkováSubject(s): Health and medicine and law
Published by: VERBUM - vydavateľstvo Katolíckej univerzity v Ružomberku
Keywords: von Willebrand factor; von Willebrand disease; Classification; Diagnosis; Treatment
Summary/Abstract: Von Willebrand disease represents the most frequent autosomally inherited bleeding disorder, with a prevalence up to 1% on the basis of epidemiological studies. The prevalence, based on the clinical significance of symptomatic patients, is most likely to be significantly lower and reaches approximately 100 per million population. Disease is caused by a deficiency and/or abnormality of von Willebrand factor (vWF), a large multimeric adhesive plasma glycoprotein, that plays an essential role in both primary and secondary hemostasis.
Journal: Zdravotnícke štúdie
- Issue Year: XI/2019
- Issue No: 1
- Page Range: 27-36
- Page Count: 10
- Language: Slovak
