Treatment Modalities of Familial Hypercholesterolemia in Children and Adolescents
Treatment Modalities of Familial Hypercholesterolemia in Children and Adolescents

Author(s): Boshra Nasser, Marwan Issa, Tatiana Kimáková
Subject(s): Health and medicine and law
Published by: Masarykova univerzita nakladatelství
Keywords: familial hypercholesterolemia; atherosclerosis; treatment;
Summary/Abstract: Familial hypercholesterolemia (FH) is an autosomal-dominant genetic disease present in all racial and ethnic groups and has long been recognized as a cause of premature atherosclerotic coronary heart disease. Heterozygous FH has the highest prevalence of genetic defects that cause significant premature mortality. An effective screening strategy together with timely initiation of established therapies would go a long way in reducing the burden of atherosclerosis due to this challenging condition.

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